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TTF1 Rabbit Monoclonal Antibody - Details |
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Production Name |
TTF1 Rabbit Monoclonal Antibody |
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Description |
Recombinant Rabbit Monoclonal Antibody |
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Conjugation |
Unconjugated |
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Modification |
Unmodified |
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Isotype |
IgG |
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Clonality |
Monoclonal |
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Form |
Liquid |
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Storage |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
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Buffer |
Purified antibody in PBS with 0.05% sodium azide,0.05% protective protein and 50% glycerol. |
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Purification |
Affinity Purification |
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Gene Name |
TTF1 |
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Gene ID |
- |
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SwissProt ID |
P43699 |
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Dilution Ratio |
WB 1:1000-1:2000,IHC 1:100-1:200,ICC/IF 1:50-1:200,ICC 1:50-1:200,FC 1:20-1:100 |
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Molecular Weight |
39 kDa |
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Alternative Names |
BCH; BHC; NK-2; TEBP; TTF1; NKX2A; TITF1; TTF-1; NKX2.1;;Nkx 2.1 |
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Research Area |
- |
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Background |
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Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation. |
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