|
TrkB Rabbit pAb |
|
Form |
Liquid |
|
Storage/Stability |
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles |
|
Immunogen |
KLH conjugated synthetic peptide derived from human NTRK2 |
|
Purification |
Affinity purified by Protein A |
|
Applications |
WB:1:500-2000,IHC-P:1:100-500,IHC-F:1:100-500,IF:1:100-500,Flow-Cyt:1μg/Test,ELISA:1:5000-10000 |
|
Gene ID |
4915 |
|
Antibody type |
Polyclonal |
|
Isotype |
IgG |
|
Immunogen range |
401-500/822 aa |
|
Molecular Weight |
90-92 kDa |
|
Subcellular Location |
Isoform TrkB is expressed in the central and peripheral nervous system. In the central nervous system (CNS), expression is observed in the cerebral cortex, hippocampus, thalamus, choroid plexus, granular layer of the cerebellum, brain stem, and spinal cord. In the peripheral nervous system, it is expressed in many cranial ganglia, the ophtalmic nerve, the vestibular system, multiple facial structures, the submaxillary glands, and dorsal root ganglia. Isoform TrkB-T1 is mainly expressed in the brain but also detected in other tissues including pancreas, kidney and heart. Isoform TrkB-T-Shc is predominantly expressed in the brain |
|
Altername |
NTRK2; Tyrosine Receptor Kinase B; Tyrosine kinase,Pyk2; BDNF tropomyosine receptor kinase B; BDNF/NT 3 growth factors receptor; BDNF/NT-3 growth factors receptor; Brain derived neurotrophic factor receptor; GP145 TrkB; GP145-TrkB; GP145-TrkB/GP95-TrkB; GP95 TrkB; Neurotrophic tyrosine kinase receptor type 2; Neurotrophin receptor tyrosine kinase type 2; NTRK 2; Ntrk2; NTRK2_HUMAN; Obesity, hyperphagia, and developmental delay, included; RATTRKB1; Trk B; Trk-B; TrkB tyrosine kinase; TRKB1; tyrosine kinase receptor B; Tyrosine receptor kinase B. |
