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TrkB Rabbit Monoclonal Antibody |
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Description |
Recombinant rabbit monoclonal antibody |
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Conjugation |
Unconjugated |
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Modification |
Unmodified |
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Isotype |
IgG |
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Clonality |
Monoclonal |
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Form |
Liquid |
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Storage |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
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Buffer |
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% protective protein. Stable for 12 months from date of receipt. |
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Purification |
Affinity Purification |
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Gene Name |
TrkB |
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Gene ID |
18212 |
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SwissProt ID |
P15209 |
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Dilution Ratio |
WB 1:1000-1:5000,IHC 1:200-1:1000,ICC/IF 1:20-1:50,IP 1:50-1:100 |
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Molecular Weight |
Calculated MW:92 kDa; Observed MW:90-140 kDa |
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Alternative Names |
Tkrb; trkB; trk-B; GP145-TrkB/GP95-TrkB |
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Background |
Receptor tyrosine kinase involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse formation and plasticity. Receptor for BDNF/brain-derived neurotrophic factor and NTF4/neurotrophin-4. Alternatively can also bind NTF3/neurotrophin-3 which is less efficient in activating the receptor but regulates neuron survival through NTRK2. |
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Validated Image |
Western blot detection of TrkB in mouse brain,Rat brain cell lysates using TrkB antibody(1:1000 diluted).
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