Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
| Description | Rabbit Monoclonal antibody |
| Alternative Names | H3K9me3; H3 histone; HIST1H3A; Histone cluster 1; H3a |
| Gene Name | H3-4 |
| Isotype | IgG |
| Application | WB,IHC-F,IHC-P,ICC/IF |
| Clonality | Monoclonal Antibody |
| Conjugation | Unconjugated |
| Modification | Methylated |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Purification | Affinity Purification |
| Gene ID | 8350 |
| SwissProt ID | P68431 |
| Dilution Ratio | WB: 1:500-1:1000 IHC: 1:50-1:100 IF: 1:50-1:200 |
| Molecular Weight | Calculated MW:15 kDa;Observed MW: 17 kDa |
Reviews
There are no reviews yet.