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TriMethyl-Histone H3 (Lys27) Rabbit Monoclonal Antibody - Details |
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Description |
Recombinant rabbit monoclonal antibody |
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Conjugation |
Unconjugated |
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Modification |
Methylated |
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Isotype |
IgG |
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Clonality |
Monoclonal |
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Form |
Liquid |
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Buffer |
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein |
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Purification |
Affinity Purification |
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Gene Name |
H3C1 |
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Alternative Names |
H3K27me3; H3 histone; HIST1H3A; Histone cluster 1; H3a |
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Gene ID |
8350 |
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SwissProt ID |
P68431 |
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Dilution Ratio |
WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200,IP 1:20-1:50,ChIP 1:20 |
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Molecular Weight |
Calculated MW: 15 kDa; Observed MW: 15 kDa |
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Storage |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
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Research Area |
Epigenetics and Nuclear Signaling |
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Background |
H3 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. |
