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TriMethyl-Histone H3-K36 - Details |
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Antibody type |
Polyclonal Antibody |
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Molecular Weight |
16kDa |
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Immunogen |
A synthetic methylated peptide corresponding to residues surrounding K36 of human histone H3 |
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Gene ID |
8290 |
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Swiss-Prot No |
Q16695 |
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Altername |
H3.4;H3/g;H3FT;H3t |
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Isotype |
IgG |
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Purification |
Affinity purification |
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Storage/Stability |
Store at -20°C. Avoid freeze / thaw cycles. |
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Buffer |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
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Dilution |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 IP 1:50 - 1:200 ChIP 1:20 - 1:100 CHIPseq 1:20 - 1:100 |
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Shipping & Stablity |
Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. |
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Background |
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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3. |
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