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SOX2 Rabbit Monoclonal Antibody - Details |
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Production Name |
SOX2 Rabbit Monoclonal Antibody |
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Description |
Recombinant Rabbit Monoclonal Antibody |
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Conjugation |
Unconjugated |
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Modification |
Unmodified |
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Isotype |
IgG |
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Clonality |
Monoclonal |
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Form |
Liquid |
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Storage |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
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Buffer |
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% protective protein. Stable for 12 months from date of receipt. |
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Purification |
Affinity Purification |
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Gene Name |
SOX2 |
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Gene ID |
6657 |
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SwissProt ID |
P48431 |
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Dilution Ratio |
WB 1:500-1:2000,IHC 1:200-1:500,ICC/IF 1:100-1:200,FC 1:500-1:1000 |
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Molecular Weight |
Calculated MW:34 kDa; Observed MW:37 kDa |
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Alternative Names |
ANOP3; MCOPS3; Transcription factor SOX-2 |
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Research Area |
- |
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Background |
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This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). |
