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Recombinant Human Toll Like Receptor 9 (TLR9) |
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Description |
Recombinant Toll Like Receptor 9 (TLR9), expressed in Escherichia coli (E. coli) and purified by standard chromatographic techniques. |
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Formulation Buffer |
PBS, pH7.4, containing 0.01% SKL, 5% Trehalose |
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Purity |
> 97% pure as determined by Silver stained SDS-PAGE analysis. Molecular Weight: ~41 KDa |
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Storage |
Shipped at 2-8°C. Aliqote and Storet at-80C; Avoid repeated freeze/thaw cycles. |
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Background |
TLR9 is activated in response to DNA, in particular DNA containing unmethylated CpG motifs that are more prevalent in microbial than mammalian DNA. By detecting foreign DNA signatures TLR9 can sense the presence of certain viruses or bacteria inside the cell and mount an immune response. |
