|
Recombinant Human Toll Like Receptor 9 (TLR9) |
|
Description |
Recombinant Human Three Prime Repair Exonuclease 1 (TREX1), expressed in Escherichia coli (E. coli) and purified by standard chromatographic techniques. |
|
Formulation Buffer |
20mM Tris, 150mM NaCl, pH8.0, containing 0.01% skl, 5%Trehalose. |
|
Purity |
> 95% pure as determined by Silver stained SDS-PAGE analysis. Molecular Weight: ~44KDa |
|
Storage |
Shipped at 2-8°C. Aliqote and Storet at-80C; Avoid repeated freeze/thaw cycles. |
|
Background |
Three Prime Repair Exonuclease 1(TREX1) acts on a single-stranded DNA polynucleotide species generated from processing of aberrant replication intermediates to attenuate DNA damage checkpoint signaling and prevent pathological immune activation. Truncated proteins retain exonuclease activity but lose normal pronuclear localization. |
