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Recombinant Human Solute Carrier Family 30 Member 8 (SLC30A8) |
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Description |
Recombinant Human Solute Carrier Family 30 Member 8 (SLC30A8), expressed in Escherichia coli (E. coli) and purified by standard chromatographic techniques. |
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Formulation Buffer |
PBS, pH7.4, containing 0.01% SKL, 5% Trehalose |
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Purity |
> 95% pure as determined by Silver stained SDS-PAGE analysis. Molecular Weight: ~32KDa |
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Storage |
Shipped at 2-8°C. Aliqote and Storet at-80C; Avoid repeated freeze/thaw cycles. |
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Background |
Solute Carrier Family 30 Member 8 (SLC30A8) is a gene that encodes a protein in humans, called Zinc transporter 8 (ZNT8). ZNT8 is a zinc transporter related to insulin secretion in humans. Certain alleles of the SLC30A8 gene may increase the risk for developing type 2 diabetes, but a loss-of-function mutation appears to greatly reduce the risk of diabetes. SLC30A8 contains a common variant (p.Trp325Arg), which is associated with T2D risk and levels of glucose and proinsulin. |
