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Recombinant Human Pro-Gastrin Releasing Peptide (ProGRP) |
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Description |
Recombinant Human Pro-Gastrin Releasing Peptide (ProGRP),expressed in Escherichia coli (E. coli) and purified by standard chromatographic techniques. |
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Formulation Buffer |
20mM Tris, 150mM NaCl, pH8.0, containing 0.01% skl, 5%Trehalose. |
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Purity |
> 95% pure as determined by Silver stained SDS-PAGE analysis. Molecular Weight: ~16KDa |
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Storage |
Shipped at 2-8°C. Aliqote and Storet at-80C; Avoid repeated freeze/thaw cycles. |
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Background |
Pro-Gastrin releasing peptide (ProGRP), a member of the bombesin family of peptides, has been shown to have mitogenic activity in small cell lung carcinoma (SCLC), and to be produced by SCLC in an autocrine fashion. The usefulness of serum pro-gastrin-releasing peptide (Pro-GRP) as a tumor marker for diagnosis, treatment and monitoring of patients with small cell lung cancer (SCLC). |
