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Recombinant Human Nucleolin (NCL) |
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Description |
Recombinant Human Nucleolin (NCL), expressed in Escherichia coli (E. coli) and purified by standard chromatographic techniques. |
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Formulation Buffer |
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300. |
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Purity |
> 90% pure as determined by Silver stained SDS-PAGE analysis. Molecular Weight: ~24KDa |
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Storage |
Shipped at 2-8°C. Aliqote and Storet at-80C; Avoid repeated freeze/thaw cycles. |
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Background |
Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It plays a role in pre-rRNA transcription and ribosome assembly. Nucleolin is also able to act as a transcriptional coactivator with Chicken Ovalbumin Upstream Promoter Transcription Factor II. |
