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Recombinant Human Nerve Growth Factor (NGF) |
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Description |
Recombinant Human Nerve Growth Factor (NGF), expressed in Escherichia coli (E. coli) and purified by standard chromatographic techniques. |
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Formulation Buffer |
20mM Tris,150mM NaCl,pH8.0,containing 1mM EDTA,1mM DTT,0.01% SKL,5% Trehalose and Proclin300. |
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Purity |
> 97% pure as determined by Silver stained SDS-PAGE analysis. Molecular Weight: ~28KDa |
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Storage |
Shipped at 2-8°C. Aliqote and Storet at-80C; Avoid repeated freeze/thaw cycles. |
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Background |
Nerve growth factor (NGF) is a neurotrophic factor and neuropeptide primarily involved in the regulation of growth, maintenance, proliferation, and survival of certain target neurons. NGF is critical for the survival and maintenance of sympathetic and sensory neurons, as they undergo apoptosis in its absence.[5] However, several recent studies suggest that NGF is also involved in pathways besides those regulating the life cycle of neurons. |
