|
Recombinant Human C Reactive Protein (CRP) |
|
Description |
Recombinant Human C Reactive Protein (CRP), expressed in Escherichia coli (E. coli) and purified by standard chromatographic techniques. |
|
Formulation Buffer |
20mM Tris, 150mM NaCl, pH8.0, containing 0.01% skl, 5%Trehalose |
|
Purity |
> 90% pure as determined by Silver stained SDS-PAGE analysis. Molecular Weight: ~27KDa |
|
Storage |
Shipped at 2-8°C. Aliqote and Storet at-80C; Avoid repeated freeze/thaw cycles |
|
Background |
C-reactive protein (CRP) is an annular (ring-shaped) pentameric protein found in blood plasma, whose circulating concentrations rise in response to inflammation. It is an acute-phase protein of hepatic origin that increases following interleukin-6 secretion by macrophages and T cells. Its physiological role is to bind to lysophosphatidylcholine expressed on the surface of dead or dying cells (and some types of bacteria) in order to activate the complement system via C1q. |