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Recombinant Dipeptidyl Peptidase IV (DPP4) |
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Description |
Recombinant Dipeptidyl Peptidase IV (DPP4), expressed in Escherichia coli (E. coli) and purified by standard chromatographic techniques. |
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Formulation Buffer |
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300. Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. |
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Purity |
> 95% pure as determined by Silver stained SDS-PAGE analysis. Molecular Weight: ~29KDa |
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Storage |
Shipped at 2-8°C. Aliqote and Storet at-80C; Avoid repeated freeze/thaw cycles. |
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Background |
DPP4 belongs to peptidase S9B family and DPPIV subfamily. It is a glycoprotein plays important role in the costimulatory signal essential for T-cell receptor-mediated T-cell activation. It’s binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. |
