| Alternative Names | NFE2L2; NRF2; Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor; erythroid derived 2; like 2 |
| Description | Recombinant Rabbit Monoclonal Antibody |
| Clonality | Monoclonal |
| Form | Liquid |
| Conjugation | Unconjugated |
| Modification | Phosphorylated |
| Isotype | IgG |
| Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification | Affinity Chromatography |
| Gene Name | NFE2L2 |
| Gene ID | 4780 |
| SwissProt ID | Q16236 |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Dilution Ratio | WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200,FC 1:50-1:100,IP 1:50-1:100 |
| Molecular Weight | Calculated MW: 68 kDa; Observed MW: 90 kDa |
Background
Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.
Research Area
Epigenetics and Nuclear Signaling
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