Background
This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described.
| Alternative Names | PAX8 |
| Description | Mouse monoclonal Antibody |
| Clonality | Monoclonal |
| Form | Liquid |
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Isotype | Mouse IgG1 |
| Buffer | Purified antibody in PBS with 0.05% sodium azide |
| Purification | Affinity Purification |
| Gene Name | PAX8 |
| Gene ID | 7849 |
| SwissProt ID | Q06710 |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Dilution Ratio | WB 1:500-1:2000,IHC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400 |
| Molecular Weight | 48.2kDa |
Research Area
MAPK Signaling Pathway
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