|
Occludin Recombinant Rabbit mAb - Details |
|
Alternative Name |
BLCPMG; PTORCH1; PPP1R115 |
|
Swiss-Prot No |
Q16625, Q61146, Q6P6T5 |
|
Recommended Dilutions |
WB: 1:1000, IHC: 1:200, ICC/IF: 1:100, FC: 1:50, IP: 1:20 |
|
Purification |
Affinity Purification |
|
Storage/Stability |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
|
Specificity |
IgG |
|
Molecular Weight |
65 kDa |
|
Immunogen |
Recombinant protein of human Occludin |
|
Conjugate |
Unconjugated |
|
Modification |
Unmodification |
|
Formulation |
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
|
Background |
|
This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. |
Reviews
There are no reviews yet.