Background
Cell localization:Cytoplasmic, Nuclear.nuclear factor, erythroid 2 like 2(NFE2L2) Homo sapiens This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene.
| Description | Rabbit Monoclonal antibody |
| Alternative Names | Nuclear factor erythroid 2-related factor 2;NF-E2-related factor 2;NFE2-related factor 2;HEBP1;Nuclear factor, erythroid derived 2, like 2 |
| Gene Name | NFE2L2 NRF2 |
| Isotype | IgG, Kappa |
| Application | WB,IHC,IF,IP,ELISA |
| Clonality | Monoclonal Antibody |
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Purification | Protein A |
| Gene ID | 4780 |
| SwissProt ID | Q16236 |
| Dilution Ratio | IHC 1:1000-1:5000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200; |
| Molecular Weight | Calculated MW:68kD;Observed MW:100kD |
| Research Area | Epigenetics and Nuclear Signaling |
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