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Nibrin Rabbit Monoclonal Antibody - Details |
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Description |
Recombinant rabbit monoclonal antibody |
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Conjugation |
Unconjugated |
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Modification |
Unmodified |
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Isotype |
IgG |
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Clonality |
Monoclonal |
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Form |
Liquid |
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Storage |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
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Buffer |
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein |
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Purification |
Affinity Purification |
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Gene Name |
NBN |
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Alternative Names |
NBN; NBS; NBS1; P95; Nibrin; Cell cycle regulatory protein p95; Nijmegen breakage syndrome protein 1 |
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Gene ID |
4683 |
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SwissProt ID |
O60934 |
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Dilution Ratio |
WB 1:500-1:1000,ICC/IF 1:50-1:200,IP 1:20-1:50 |
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Molecular Weight |
Calculated MW: 85 kDa; Observed MW: 95 kDa |
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Research Area |
Epigenetics and Nuclear Signaling |
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Background |
NBS1 is a member of the MRE11/RAD50 double-strand break repair complex. Involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. Mutation results in the Nijmegen breakage syndrome (NBS), an autosomal recessive chromosomal instability syndrome. |
