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Myogenin Rabbit Polyclonal Antibody |
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Gene Name |
MYOG |
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Protein Name |
Myogenin |
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Human Gene Id |
4656 |
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Swiss-Prot No |
P15173 |
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Mouse Gene Id |
17928 |
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Mouse Swiss Prot No |
P12979 |
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Rat Gene Id |
29148 |
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Rat Swiss Prot No |
P20428 |
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Immunogen |
The antiserum was produced against synthesized peptide derived from human Myogenin. AA range:50-99 |
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Specificity |
Myogenin Polyclonal Antibody detects endogenous levels of Myogenin protein |
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Concentration |
1 mg/ml |
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Recommended Dilutions |
IHC-p: 100-300.WB 1:500 - 1:2000. ELISA: 1:10000.. IF 1:50-200 |
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Alternative Names |
MYOG; BHLHC3; MYF4; Myogenin; Class C basic helix-loop-helix protein 3; bHLHc3; Myogenic factor 4; Myf-4 |
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Predicted Molecular Weight |
39kD |
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Form of Antibody |
Liquid |
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Storage/Stability |
Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles |
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Source |
Polyclonal, Rabbit,IgG |
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Tissue Expression |
Eye,Skeletal muscle |
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Cellular localization |
Nucleus. Recruited to late myogenic gene promoter regulatory sequences with SMARCA4/BRG1/BAF190A and SWI/SNF chromatin-remodeling enzymes to promote chromatin-remodeling and transcription initiation in developing embryos |
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Function |
Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein |
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Purification |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
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Background |
Myogenin is a muscle-specific transcription factor that can induce myogenesis in a variety of cell types in tissue culture. It is a member of a large family of proteins related by sequence homology, the helix-loop-helix (HLH) proteins. It is essential for the development of functional skeletal muscle |
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Validated Image |
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