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FITC Anti-Mouse CD3 Antibody(17A2) - Details |
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Synonyms |
CD3| CD3E/D/G/Z| CD3e/d/g/z| T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain antibody |
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Clonality |
Monoclonal |
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Isotype |
IgG2b, κ |
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Form |
Liquid |
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Concentration |
0.2mg/mL |
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Conjugation |
FITC |
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Conjugation |
FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter). |
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Clone ID |
17A2 |
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Storage |
PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
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Alternative Names |
CD3| CD3E/D/G/Z| CD3e/d/g/z| T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain antibody |
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UniProt ID |
P04235 P11942 P22646 P24161 |
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Recommended dilution |
The recommended concentration is 0.1-1μg/10⁶ cells in 100 μL volume] |
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Background |
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CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex. |
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