UniPort summary Function
Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration.
| Altername | DC; DBCN; LISX; SCLH; XLIS |
| Background | Swiss-Prot Acc.O43602. |
| Clone Number | Polyclonal antibody |
| Immunogen | Recombinant protein of human Doublecortin |
| Isotype | Rabbit IgG |
| Purification | Affinity purified |
| Gene Name | DCX |
| Antibody type | Primary antibody |
| Recommended Dilutions | WB: 1:1000; IHC: 1:20; ICC/IF: 1:50 |
| Gene ID | 1641 |
| Molecular Weight | Calculated MW: 41 kDa; Observed MW: 41 kDa |
| Swiss-Prot No | O43602 |
| Form of Antibody | Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. |
| Storage/Stability | Store at -20°C. Stable for 12 months from date of receipt. |