Background
Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control.
| Production Name | Cyclin B2 Rabbit Monoclonal Antibody |
| Description | Rabbit Monoclonal antibody |
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Isotype | IgG |
| Clonality | Monoclonal Antibody |
| Form | Liquid |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Buffer | Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% protective protein . Stable for 12 months from date of receipt. |
| Purification | Affinity purification |
| Gene Name | Cyclin B2 |
| Alternative Names | HsT17299 |
| Gene ID | 9133 |
| SwissProt ID | O95067 |
| Dilution Ratio | WB: 1:1000 IHC-P: 1:100 ICC/IF: 1:200-1:500 IP: 1:50-1:100 |
| Molecular Weight | Calculated MW:45 kDa; Observed MW:45 kD |
| Research Area | Cell Biology |