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CLU Antibody - Details |
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Synonyms |
Clusterin|Aging-associated gene 4 protein|Apolipoprotein J (Apo-J)|Complement cytolysis inhibitor (CLI)|Complement-associated protein SP-40 antibody, 40|Ku70-binding protein 1|NA1/NA2|Sulfated glycoprotein 2 (SGP-2)|Testosterone-repressed prostate message 2 (TRPM-2)|Clusterin beta chain Alternative names: ApoJalpha|Complement cytolysis inhibitor a chain|SP-40 antibody, 40 beta-chain|Clusterin alpha chain Alternative names: ApoJbeta|Complement cytolysis inhibitor b chain|SP-40 antibody, 40 alpha-chain|CLU|APOJ|CLI|KUB1 antibody |
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Clonality |
Monoclonal |
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Isotype |
IgG2a |
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Form |
Liquid |
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Purification |
Protein A+G purification |
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Purity |
ā„95% as determined by SDS-PAGE |
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Clone ID |
5A5 |
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Storage |
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20ā for 12 months(Avoid repeated freeze / thaw cycles.) |
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Immunogen |
Clusterin |
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UniProt ID |
P10909 |
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Observed MW |
36 kDa |
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Recommended dilution |
WB: 1:500-1:2000; IHC: 1:20-1:200 |
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Background |
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Clusterin (Apolipoprotein J) is a 75-80 kDa heterodimeric glycoprotein produced by a wide array of tissues and found in most biologic fluids (PMID: 7648419; 11906815). It is encoded by one single gene and cleaved posttranslationally into Ī± (34-36 kDa) and Ī² (36-39 kDa) subunits prior to secretion from the cell. Many functions have been described for clusterin, including regulating apoptosis, transporting lipids, controlling cell interactions, regulating complemen |
