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Claudin 5 Recombinant Rabbit mAb - Details |
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Alternative Name |
AWAL; BEC1; TMVCF; CPETRL1 |
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Swiss-Prot No |
O00501, O54942 |
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Recommended Dilutions |
WB: 1:1000-1:10000, IHC: 1:200-1:1000, ICC/IF: 1:1000 |
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Formulation |
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
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Purification |
Affinity Purification |
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Storage/Stability |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
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Specificity |
IgG |
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Molecular Weight |
23 kDa |
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Immunogen |
A synthetic peptide of human Claudin 5 |
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Conjugate |
Unconjugated |
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Modification |
Unmodification |
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Background |
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This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene. |
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