Choline Chloride

CAS No: 67-48-1

Catalouge No C7527
Linear Formula (CH3)3N(Cl)CH2CH2OH
Molecular Weight 139.62
Form Crystals
Size 100 GM
Price POR
Manufacturer Sigma-Aldrich® Solutions
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SKU: C7527 Categories: ,

BioReagent, suitable for cell culture, suitable for insect cell culture, ≥98%

Choline chloride is a quaternary ammonium salt and associates with hydrogen bond donors (HBD).[1] It is essential for the vital physiological functions and is used as a nutritional additive. Choline is a source of methyl groups for methyl-transfer reactions.

biological source synthetic (organic)
product line BioReagent
Assay ≥98%
technique(s) cell culture | insect: suitable, cell culture | mammalian: suitable, cell culture | plant: suitable
color white
pH 5.0-6.5 (25 °C, 140 g/L)
mp 302-305 °C (dec.) (lit.)
solubility H2O: 50 mg/mL
SMILES string [Cl-].C[N+](C)(C)CCO
InChI 1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1
InChI key SGMZJAMFUVOLNK-UHFFFAOYSA-M

Safety Information

  • Storage Class Code: 11 – Combustible Solids
  • WGK: WGK 1
  • Flash Point(F): Not applicable
  • Flash Point(C): Not applicable
  • Personal Protective Equipment: dust mask type N95 (US), Eye shields, Gloves

Choline chloride has been used:

  • as a component of choline acetyltransferase (ChAT) buffer and for choline uptake in cultured human neuroblastoma (SK-N-SH) cells[3]
  • for choline standard curve generation for quantifying phospholipase D (PLD) activity[4]
  • as a component of slice solution for the dissection of entorhinal-hippocampal brain slices[5]

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