| Caspase-9 Rabbit Monoclonal Antibody | |
| Description | Recombinant Rabbit Monoclonal Antibody |
| Applications | WB,ICC/IF,ELISA |
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Isotype | IgG, Kappa |
| Clonality | Monoclonal |
| Form | Liquid |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%protective protein |
| Purification | Protein A |
| Gene Name | CASP9 |
| Gene ID | 842 |
| SwissProt ID | P55211 |
| Alternative Names | CASP9;MCH6;Caspase-9;CASP-9;Apoptotic protease Mch-6;Apoptotic protease-activating factor 3;APAF-3;ICE-like apoptotic protease 6;ICE-LAP6 |
| Dilution Ratio | WB 1:1000-1:5000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000 |
| Molecular Weight | Calculated MW:46kD;Observed MW:40kD |
Caspase-9 Rabbit Monoclonal Antibody
| Catalogue No | BSAB-249P |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Size | 20μL | 50μL | 100μL |
| Price | POR |
Cell localization:Cytoplasm.This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.
Western blot analysis of lysates from Hela cells, using Caspase-9 Rabbit mAb. The HRP-conjugated Goat anti-Rabbit IgG antibody was used to detect the antibody