Background
This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Alternative splicing results in multiple transcript variants.
| Altername | CR; CAL2; CAB29 |
| Recommended Dilutions | WB: 1:1000 : IHC: 1:20-1:100 : ICC/IF: 1:20-1:50 : FC: 1:20 |
| Purification | Affinity Purification |
| Molecular Weight | 32 kDa |
| Immunogen | A synthetic peptide of human Calretinin |
| Specificity | IgG |
| Conjugate | Unconjugated |
| Modification | Unmodification |
| Swiss-Prot No | P22676 |
| Storage/Stability | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
| Formulation | Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |