| Bosutinib, ≥98% (HPLC) | |
| Synonyms | 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile, SKI-606, WAY-173606 |
| Grade | HPLC |
| Categories | Cell biology, Bioactive small molecules |
| Assay (HPLC) | ≥98% |
| Appearance (Form) | Powder |
| Appearance (Colour) | Off white to beige |
| Storage temp. | Room temp |
| HSN Code | 29420090 |
| Pack Size | 5 MG | 100 MG |
| Bosutinib, ≥99% Cell Culture | |
| Appearance | White to yellow Solid |
| Grade | Cell Culture |
| Solubility | Soluble in DMSO |
| Purity | ≥99% |
| SMILES | CN1CCN(CC1)CCCOC2=C(C=C3C(NC4=CC(OC)=C(C=C4Cl)Cl)=C(C=NC3=C2)C#N)OC |
| InChIKey | UBPYILGKFZZVDX-UHFFFAOYSA-N |
| InChI | InChI=1S/C26H29Cl2N5O3/c1-32-6-8-33(9-7-32)5-4-10-36-25-13-21-18(11-24(25)35-3)26(17 (15-29)16-30-21)31-22-14-23(34-2)20(28)12-19(22)27/h11-14, 16H, 4-10H2, 1-3H3, (H, 30, 31) |
| Target Point | Src;Abl |
| Passage | Protein Tyrosine Kinase/RTK |
| Background | Bosutinib is a dual inhibitor of Src/Abl. |
| Biological Activity | Bosutinib (SKI-606) is a dual Src/Abl inhibitor with IC50s of 1.2 nM and 1 nM, respectively |
| Storage | Powder:2-8℃, 2 years;Insolvent(Mother Liquid):-20℃, 6 months;-80℃, 1 year |
| Pack Size | 1 MG | 5 MG | 10 MG | 25 MG |
Bosutinib
CAS No: 380843-75-4
| Catalogue No | BSCHM-047B |
| Mol. Formula | C26H29Cl2N5O3 |
| Mol. Weight | 530.45 |
| Price | POR |
Bosutinib (SKI-606) is an orally active; dual Src/Abl tyrosine kinase inhibitor with potent antiproliferative activity.
Bosutinib, ≥98% (HPLC) - used in chemical research.
- WGK Germany 3