Description

PRODUCT INFORMATION

Size:  100µg

Form:  liquid

Purification:  Immunogen affinity purified

Purity:  ≥95% as determined by SDS-PAGE

Clonality:  polyclonal

Storage:  PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen:  toll-like receptor 4

Synonyms:  ARMD10, CD284, hToll, TLR4, TOLL, toll like receptor 4

Observed MW:  95 kDa

APPLICATION

Tested Application:  ELISA, WB, IHC

Recommended Dilution:  WB: 1:500 – 1:2000; IHC: 1:100 – 1:200

IMAGES:-

	Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using BS-72780 BANF( TLR4 Antibody) at dilution of 1:200
	mouse liver tissue were subjected to SDS PAGE followed by western blot with BS-72780 BANF( TLR4 Antibody) at dilution of 1:1000

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Additional Information