Anti- TLR4 Antibody

Synonyms ARMD10, CD284, hToll, TLR4, TOLL, toll like receptor 4
Catalogue No BS-72780BANF
Reactivity Human, Hamster, Mouse
Host Rabbit
Tested Application ELISA, IHC, WB
Clonality Polyclonal
Isotype IGC
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SKU: BS-72780BANF Categories: ,

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.

Size 100µg
Form Liquid
Purification Immunogen affinity purified
Purity ≥95% as determined by SDS-PAGE
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
IMMUNOGEN INFORMATION
Immunogen toll-like receptor 4
Synonyms ARMD10, CD284, hToll, TLR4, TOLL, toll like receptor 4
Observed MW 95 kDa
APPLICATION
Tested Application ELISA, WB, IHC
Recommended Dilution WB: 1:500 – 1:2000; IHC: 1:100 – 1:200


Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using BS-72780 BANF( TLR4 Antibody) at dilution of 1:200


mouse liver tissue were subjected to SDS PAGE followed by western blot with BS-72780 BANF( TLR4 Antibody) at dilution of 1:1000

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