Description
| PRODUCT INFORMATION | |
| Product Name | anti- IL1 Beta antibody |
| Catalogue No. | BSMAB04210 |
| Size | 100µg |
| Form | liquid |
| Purification | Protein G purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Host | Mouse |
| Clonality | monoclonal |
| Isotype | IgG1 |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
BACKGROUND
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
IMMUNOGEN INFORMATION
Immunogen: interleukin 1, beta
Synonyms: IL1 beta, Catabolin, IL 1, IL 1 beta, IL1 BETA, IL1B, IL1beta, IL1F2, IL-1β, Interleukin 1 beta, interleukin 1, beta
Observed MW:35kDa
- Tested Application: ELISA, IHC, WB
- Recommended Dilution: WB: 1:1000-1:4000; IHC: 1:50-1:500
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