|
Anti-BNP Polyclonal Antibody |
|
Gene ID |
4879 |
|
Clone Type |
Polyclonal Antibody |
|
Subtype |
IgG |
|
Dilution Ratio |
WB 1:1000-5000. IHC-P 1:50-200. IF/ICC 1:50-200. |
|
Target |
BNP |
|
Swiss Prot |
P16860 |
|
Subcellular Location |
Secreted |
|
Immunogen |
A synthetic peptide of human BNP |
|
Public Immunogen Range |
35-134aa |
|
Calculated MW |
14kDa |
|
Observed MW |
15kDa |
|
Purification Method |
Affinity purification |
|
Storage Buffer |
PBS with 0.05% proclin300,50% glycerol,pH7.3. |
|
Background |
This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis |