Angelicin

Catalouge No BSCFN-98854
Product Name Angelicin
CAS 523-50-2
Size 10 mM * 100 uL | 10 mM * 1 mL
Molecular Formula C11H6O3
Molecular Weight 186.2 g/mol
Purity >=98%
Type of Compound Coumarins
Physical Desc Powder
Source The seeds of Psoralea grandulosa
Solvent Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone
Targets p65 | NF-kB | IkB | p38MAPK | JNK | Bcl-2/Bax | Caspase | PI3K | Akt | GSK-3 | Antifection | IKK
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Angelicin has anti-cancer, antiviral, and anti-inflammatory activities; it regulates LPS-induced inflammation via inhibiting MAPK/NF-κB pathways. Angelicin is a powerful inducer of erythroid differentiation and -globin mRNA accumulation of human leukemia K562 cells, it is a potential therapeutic approach in hematological disorders, including -beta-thalassemia and sickle cell anemia.

Storage

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

After Receiving

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

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