Alix Recombinant Rabbit Monoclonal Antibody (JM85-31)

Catalogue no MA5-32773
Species reactivity Human, Mouse, Rat
Host/isotype Rabbit / IgG
Class Recombinant Monoclonal
Type Antibody
Clone JM85-31
Size 100 µL
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SKU: MA5-32773 Categories: ,
Immunogen Recombinant protein within Human ALIX aa 1-160
Conjugate Unconjugated
Excitation/Emission Max 498/517 nm
Form Liquid
Concentration 1 mg/mL
Purification Protein A
Storage buffer TBS, pH 7.4, with 40% Glycerol, 0.05% BSA
Contains 0.05% sodium azide
Storage conditions Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions Ambient (domestic); Wet ice (international)
RRID AB_2810050
Storage conditions Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Manufacturer Thermo Fisher Scientific

Product Specific Information

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Apoptotic linked-gene-product 2 (ALG-2) interacting protein X (ALIX) is a conserved adaptor protein which is ubiquitously expressed. Alix was originally reported to play a role in apoptosis but has recently been shown to be involved in other cellular mechanisms including endosomal sorting, endocytosis, viral budding and actin cytoskeleton assembly.

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