| Adenosine A2A-R Rabbit Polyclonal Antibody - Details | |
| Description | Rabbit Polyclonal Antibody |
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Isotype | IgG |
| Clonality | Polyclonal |
| Form | Liquid |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Buffer | Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% New type preservative N. |
| Purification | Affinity purification |
| Gene Name | ADORA2A |
| Alternative Names | ADORA2A; ADORA2; Adenosine receptor A2a |
| Gene ID | 135 |
| SwissProt ID | P29274 |
| Dilution Ratio | WB 1:500-1:2000,IHC 1:100-1:300,ICC/IF 1:200-1:1000,ELISA 1:5000-1:10000 |
| Molecular Weight | 37kDa |
| Research Area | Calcium;Neuroactive ligand-receptor interaction;Vascular smooth muscle contraction |
| Background | adenosine A2a receptor(ADORA2A) Homo sapiens This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily, which is subdivided into classes and subtypes. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein, an adenosine receptor of A2A subtype, uses adenosine as the preferred endogenous agonist and preferentially interacts with the G(s) and G(olf) family of G proteins to increase intracellular cAMP levels. It plays an important role in many biological functions, such as cardiac rhythm and circulation, cerebral and renal blood flow, immune function, pain regulation, and sleep. It has been implicated in pathophysiological conditions such as inflammatory diseases and neurodegenerative disorders. Alternative splicing results in multiple transcript variants. A read-through transcript composfunction: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase., similarity: Belongs to the G-protein coupled receptor 1 family |
Adenosine A2A-R Rabbit Polyclonal Antibody
| Catalouge No | BSAB-241P |
| Host | Rabbit |
| Reactivity | Human, Rat, Mouse |
| Applications | WB,IHC,ICC/IF,ELISA |
| Size | 20μL | 50μL | 100μL | 200μL |
| Price | POR |
Immunofluorescence analysis of COS7 cells, using ADORA2A Antibody. The picture on the right is blocked with the synthesized peptide.
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using ADORA2A Antibody. The picture on the right is blocked with the synthesized peptide
Western blot analysis of ADORA2A Antibody. The lane on the right is blocked with the ADORA2A peptide.
Immunofluorescence analysis of ADORA2A Antibody. The lane on the right is blocked with the ADORA2A peptide.
Western blot analysis of the lysates from HepG2 cells using ADORA2A antibody