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RNF8 Rabbit Monoclonal Antibody

RNF8 Rabbit Monoclonal Antibody

Catalogue No BSAB-245P
Host Rabbit
Reactivity Human, Rat
Size 20μL | 50μL | 100μL
Price POR
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SKU: BSAB-245P Categories: ,
RNF8 Rabbit Monoclonal Antibody
Description Recombinant Rabbit Monoclonal Antibody
Applications WB
Conjugation Unconjugated
Modification Unmodified
Isotype IgG
Clonality Monoclonal
Form Liquid
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer Purified antibody in PBS with 0.05% sodium azide,0.05% protective protein and 50% glycerol.
Purification Affinity purification
Gene Name RNF8
Gene ID -
SwissProt ID O76064
Alternative Names C3HC4 type zinc finger protein; RNF8;;RNF8
Dilution Ratio WB 1:1000-1:2000
Molecular Weight Calculated MW: 56 kDa ; Observed MW: 60 kDa

E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites.


Western blot analysis of RNF8 expression in human fetal kidney lysate.