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488 Anti-Mouse CD127/IL-7RA Antibody(A7R34)

488 Anti-Mouse CD127/IL-7RA Antibody(A7R34)

Catalogue No BSPC-028FA
Host Rat
Reactivity Mouse
Size 50 T | 100 T
Price POR
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SKU: BSPC-028FA Categories: ,
488 Anti-Mouse CD127/IL-7RA Antibody (A7R34)
Alternative Names CD127|IL-7 receptor subunit alpha|IL-7R subunit alpha|IL-7R-alpha|IL-7RA|Il7r|Interleukin-7 receptor subunit alpha antibody
Applications FC
Clonality Monoclonal
Isotype IgG2a, κ
Form Liquid
Conjugation 488
Conjugation Information 488 is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 520 nm (e.g., a 525/40 nm bandpass filter).
Clone ID A7R34
Storage PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)
UniProt ID P16872
Recommended dilution Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use
Background CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be an useful marker for identifying memory and effector T cells. Theligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cells proliferation and development.

C57BL/6 murine splenocytes are stained with FineTest® 488 Anti-Mouse CD127/IL-7RA Antibody (filled gray histogram). Unstained splenocytes (black histogram) are used as control.