|
Recombinant Human IL-18.docx |
|
Description |
Recombinant Human Interleukin-18 (IL-18),expressed in Escherichia coli (E. coli) and purified by standard chromatographic techniques and supplied as Freeze-dried powder. The protein contains two N-terminal His-tag. |
|
Formulation Buffer |
20mM Tris, 150mM NaCl, pH8.0, containing 1mMEDTA, 1mM DTT, 0.01% sarcosyl, 5%Trehalose and Proclin300. Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0mg/mL. Do not vortex. |
|
Purity |
> 90% pure as determined by Silver stained SDS-PAGE analysis. Molecular Weight: ~18KDa |
|
Storage |
Shipped at 2-8°C. Aliqote and Storet at-80C; Avoid repeated freeze/thaw cycles. |
|
Background |
Interleukin 18 is a proinflammatory cytokine in IL-1 family and can induce the IFN gamma production of T cells. Interleukin 18 (IL-18) binds to a heterodimeric receptor consisting of IL-18R and IL-18 receptor accessory protein, leading to the activation of NF-kB and AP-1 |
