|
Recombinant Human Major basic protein(MBP) |
|
Description |
Expressed in Escherichia coli (E. coli) and purified by standard chromatographic techniques |
|
Formulation Buffer |
20mM Tris, 150mM NaCl, pH8.0, containing 0.01% skl, 5%Trehalose. |
|
Purity |
> 90% pure as determined by Silver stained SDS-PAGE analysis. Molecular Weight: ~44KDa |
|
Storage |
Shipped at 2-8°C. Aliqote and Storet at-80C; Avoid repeated freeze/thaw |
|
Background |
Major basic protein (MBP) is an eosinophil granule protein. Eosinophil granules contain a crystalloid core comprised of MBP and a matrix consisting of other toxic and pro-inflammatory mediators. Increased concentrations of MBP and other cationic proteins have shown correlations with atopic diseases, parasitic infections, and other eosinophil-associated inflammatory processes. |
