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Neuron-specific class III β-tubulin Antibody - Details |
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Clone Number |
No:A8-D10 |
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Positive control |
Hela |
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Swiss-Prot No |
Q13509/Q9ERD7 |
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Project ID |
M080514 |
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Form of Antibody |
Mouse monoclonal IgG2a in 1*TBS (pH7.4), 0.5%BSA, 25%Glycerol. Preservative: 0.05% Sodium Azide. |
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Storage/Stability |
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
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Specificity/Sensitivity |
This antibody is produced by immunizing mouse with a synthetic peptide (KLH-coupled) corresponding to the near of N-terminal residues of neuro-specific class III β-tubulin |
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Molecular Weight |
50kDa |
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Background |
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Tubulin is a compound of subunits of A tubulin and B tubulin. Class III beta tubulin (beta III-tubulin) is a vertebrate tubulin isotype specific to the neurons and mammalian testis cells, making it an ideal neuronal marker. Overexpression of class III beta tubulin is associated with the resistances of microtubule-targeted cancer drugs in lung cancer cell lines, breast cancer cell lines, and ovarian tumors. |
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