|
KLF4 Rabbit Monoclonal Antibody - Details |
|
Production Name |
KLF4 Rabbit Monoclonal Antibody |
|
Description |
Recombinant Rabbit Monoclonal Antibody |
|
Conjugation |
Unconjugated |
|
Modification |
Unmodified |
|
Isotype |
IgG, Kappa |
|
Clonality |
Monoclonal |
|
Form |
Liquid |
|
Storage |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
|
Buffer |
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%protective protein |
|
Purification |
Protein A |
|
Gene Name |
KLF4 |
|
Gene ID |
9314 |
|
SwissProt ID |
O43474 |
|
Dilution Ratio |
WB 1:1000-1:5000,IHC 1:200-1:1000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200 |
|
Molecular Weight |
Calculated MW:55kD;Observed MW:60kD |
|
Alternative Names |
KLF4;EZF;GKLF;Krueppel-like factor 4;Epithelial zinc finger protein EZF;Gut-enriched krueppel-like factor |
|
Research Area |
- |
|
Background |
|
Cell localization:Nuclear.This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is required for normal development of the barrier function of skin. The encoded protein is thought to control the G1-to-S transition of the cell cycle following DNA damage by mediating the tumor suppressor gene p53. Mice lacking this gene have a normal appearance but lose weight rapidly, and die shortly after birth due to fluid evaporation resulting from compromised epidermal barrier function. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Reviews
There are no reviews yet.