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CD45 Antibody

Catalouge No BSPU-014FA
Host Mouse
Reactivity Human, Pig
Applications ELISA, WB, IHC, FC
Size 100µg
Price POR
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SKU: BSPU-014FA Categories: ,
CD45 Antibody - Details
Synonyms Receptor-type tyrosine-protein phosphatase C|Leukocyte common antigen (L-CA)|T200|PTPRC|CD45 antibody
Isotype IgG2a
Form Liquid
Purification protein A+G purified
Purity ≄95% as determined by SDS-PAGE
Clonality Monoclonal
Clone ID 4C8
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20ā„ƒ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID P08575
Recommended dilution WB: 1:1000-1:10000; IHC: 1:20-1:200
Observed MW 180-220 kDa
Background
CD45, also known as leukocyte common antigen(LCA), B220, and T200, is a 180-240 kD single chain type I membrane glycoprotein. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes and platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation.