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CTGF Rabbit Polyclonal Antibody - Details |
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Description |
Rabbit Polyclonal Antibody |
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Conjugation |
Unconjugated |
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Modification |
Unmodified |
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Isotype |
IgG |
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Clonality |
Polyclonal |
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Form |
Liquid |
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Storage |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
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Buffer |
Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% New type preservative N. |
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Purification |
Affinity purification |
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Gene Name |
CTGF CCN2 HCS24 IGFBP8 |
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Alternative Names |
Connective tissue growth factor (CCN family member 2;Hypertrophic chondrocyte-specific protein 24;Insulin-like growth factor-binding protein 8;IBP-8;IGF-binding protein 8;IGFBP-8) |
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Gene ID |
1490 |
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SwissProt ID |
P29279 |
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Dilution Ratio |
IHC 1:50-1:200,ICC/IF 1:50-1:200,ELISA 1:10000-1:20000 |
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Research Area |
Cardiovascular |
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Background |
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The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis. [provided by RefSeq, Nov 2009],function: Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. similarity: Belongs to the CCN family. similarity: Contains 1 CTCK (C-terminal cystine knot-like) domain. similarity: Contains 1 IGFBP N-terminal domain. similarity: Contains 1 TSP type-1 domain, similarity: Contains 1 VWFC domain. subunit: Monomer |
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