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APC Anti-Mouse CD3 Antibody(17A2) - Details |
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Synonyms |
CD3| CD3E/D/G/Z| CD3e/d/g/z| T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain antibody |
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Clonality |
Monoclonal |
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Isotype |
IgG2b, κ |
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Form |
Liquid |
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Concentration |
0.2mg/mL |
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Conjugation |
APC |
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Conjugation Information |
APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter). |
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Clone ID |
17A2 |
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Storage |
PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
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Alternative Names |
CD3| CD3E/D/G/Z| CD3e/d/g/z| T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain antibody |
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UniProt ID |
P04235 P11942 P22646 P24161 |
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Recommended dilution |
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Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1μg/10⁶ cells in 100 μL volume]. |
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Background |
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CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex. |
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