Diosgenin

CAS No: 512-04-9

Catalouge No BSCHM-011D
Mol. Formula C27H42O3
Mol. Weight 414.63 g/mol
Purity >=98%
Size 20 MG
Price POR
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SKU: BSCHM-011D Categories: ,
Product Name Diosgenin
Type of Compound Steroids
Physical Desc. Powder
Source The rhizomes of Dioscorea zingiberensis C.H.Wright
Solvent DMSO, Pyridine, Methanol, Ethanol, etc.
CAS No 512-04-9
Targets PKA | cAMP | Akt | p38MAPK | Phospholipase (e.g. PLA) | ERK | JNK | NOS | COX | AP-1 | Bcl-2/Bax | MMP(e.g.TIMP) | TNF-α | NF-kB | p65 | HIV | ApoE4

Biological Activity

Diosgenin possesses ant vascular calcification , anti-osteoclast genesis, anti-inflammatory and anticancer properties, it has favorable effects in the improvement of diabetes and regulation of lipid metabolism. Diosgenin treated inflammation-related disorders through the blockade of cAMP, PKA, cPLA2, PAK, Akt and MAPKs signaling pathways. Diosgenin may decrease the risk of developing dementia of opiate abusers with HIV infection and the ApoE4 allele.

Storage

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

After Receiving

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

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