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BioString™ RNA Mini Column

BioString™ RNA Mini Column

Catalogue No BS-RNA-053
Product Name
BioStringTM RNA Mini Column
Size 1000/Bag
Price POR
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Feature Specifications
Recommended application Plasmid Mini Preparation, gDNA/ RNA Extraction, DNA/RNA Clean Up
Preservation conditions Room temperature
Stability Up to 4 years
Filter membrane High quality glass fiber filter GF/B, 3 layers
Membrane aperture 1.0μm
Maximum binding yield of plasmid 30 μg
Maximum yield of alcohol mediated Binding 200 μg
Single liquid carrying capacity of column 800 μl
Minimum elution volume 30 μl
Withstand centrifugal force 16,000 x g
Centrifuge Small high speed centrifuge (2ml)

Although the adsorption mechanism remains the same as DNA columns, this format is used in RNA-focused workflows where consistency and recovery of total RNA are required.

It is commonly used in RNA cleanup steps or integrated into RNA extraction systems where the column structure needs to handle aqueous RNA conditions without compromising binding stability.

Based on the negatively charged DNA skeleton, it has a high affinity for positively charged glass fibers. In high salt and ethanol solutions, DNA/RNA binds to glass fiber and interacts with hydrophilic matrix on silica through hydrogen bond. DNA/RNA is tightly bound. All pollutants can be removed by washing solution. At high salt concentration, nucleic acids selectively bind to silicagel membrane, while other pollutants, mainly proteins, are removed by membrane washing.