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LMX1A Antibody |
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Description |
Rabbit polyclonal antibody to LMX1A |
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Application |
IF/ICC 1:100-1:500, WB 1:500-1:2000, IHC 1:50-1:200 |
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Clonality |
Polyclonal |
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Specificity |
LMX1A Antibody detects endogenous levels of total LMX1A. |
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Conjugate |
Unconjugated. |
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Purification |
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin. |
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Storage |
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt. |
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Immunogen |
A synthesized peptide derived from human LMX1A, corresponding to a region within the internal amino acids. |
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Uniprot |
Q8TE12(LMX1A_HUMAN) |
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Gene(ID) |
LMX1A(4009) |
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Subcellular Location |
Nucleus. |
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Function |
Acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. Required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae (By similarity). |
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Prediction |
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance. |
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Validated Image |
Western blot analysis of lysates from Hela cells(heat-shock,45min treatment), using LMX1A Antibody at 1/1000 dilution.
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