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Bad Rabbit Monoclonal Antibody

Bad Rabbit Monoclonal Antibody

Catalogue No BSAB-314P
Host Rabbit
Reactivity Human Mouse, Rat
Applications WB,IHC,ICC/IF,ELISA,IP
Size 20μL | 50μL | 100μL
Price POR
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SKU: BSAB-314P Categories: ,
Bad Rabbit Monoclonal Antibody
Description Recombinant Rabbit Monoclonal Antibody
Conjugation Unconjugated
Modification Unmodified
Isotype IgG, Kappa
Clonality Monoclonal
Form Liquid
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%protective protein
Purification Protein A
Gene Name BAD
Gene ID 572
SwissProt ID Q92934
Alternative Names BAD;BBC6;BCL2L8;Bcl2 antagonist of cell death;BAD;Bcl-2-binding component 6;Bcl-2-like protein 8;Bcl2-L-8;Bcl-XL/Bcl-2-associated death promoter
Buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%protective protein
Molecular Weight Calculated MW:18kD;Observed MW:23kD
Background Cell localization:Cytoplasm.The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
Validated Image

A431 cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with RAGE Rabbit Monoclonal Antibody 1:1000. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody.

Immunohistochemical analysis of paraffin-embedded Human kidney tissue. 1, Bad Rabbit Monoclonal Antibody was diluted at 1:200(4°C,overnight). 2, EDTA pH 9.0 was used for antibody retrieval(>98°C,20min). 3,Secondary antibody was diluted at 1:200