|
Bcl-2 Recombinant Rabbit mAb |
|
Conjugation |
Unconjugated |
|
Modification |
Unmodification |
|
Altername |
IgG |
|
Specificity |
IgG |
|
Immunogen |
Bcl-2; PPP1R50 |
|
Recommended Dilutions |
WB: 1:1000 IHC: 1:200-1:500 IP: 1:50 |
|
Purification |
Affinity Purification |
|
Molecular Weight |
26 kDa |
|
Formulation |
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
|
Storage/Stability |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
|
Background |
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. |
